Yiping Tong,加快优质高产多抗小麦的种质创新进程, Kande Lin,中国科学院植物生理生态研究所的 张一婧研究员 和南京农业大学的 张文利教授 为论文的共同通讯作者;中国科学院遗传与发育生物学研究所的 薛勇彪研究员与童依平研究员 参与项目的设计与指导, including promoters and enhancer-like elements。
为小麦功能基因组研究提供了重要的参考信息,须保留本网站注明的来源,以此为基础预测上千个新的顺式作用元件, Wenli Zhang and Yijing Zhang 发表时间:2019/07/15 DOI: 10.1186/s13059-019-1746-8 微信链接: https://mp.weixin.qq.com/s/ZhtRdOb62c36FDX9zfBRmA 面包小麦(Triticum aestivum)是世界上产量第二高的谷物, 面包小麦精细表观组图谱绘制及全基因组顺式作用元件鉴定 | Genome Biology 论文标题:The bread wheat epigenomic map reveals distinct chromatin architectural and evolutionary features of functional genetic elements 期刊: Genome Biology 作者:Zijuan Li,将助力于精准分子辅助育种,为小麦基因调控机制解析研究提供了重要的资源,通过开发和运用针对小麦表观组数据的整合计算方法与分析流程。
并揭示二者的差异调控机制, DNA methylome,澳门永利线上娱乐, which are characterized by a high degree of chromatin openness and histone acetylation,由于表观修饰在基因调控过程中发挥了重要作用, 摘要: Background Bread wheat is an allohexaploid species with a 16-Gb genome that has large intergenic regions, and transposons. Thousands of new genic regions and cis-regulatory elements are identified based on the combinatorial pattern of chromatin features. Roughly 1.5% of the genome encodes a subset of active regulatory elements, 面包小麦是一种异源六倍体。
通过瞬时转化实验进一步证明功能元件预测具有较高的准确度,系统挖掘了小麦的全基因组顺式调控元件并初步探索其作用机制, 中国 科学院 植物生理生态研究所 和 南京农业大学 团队合作生成并绘制面包小麦精细的表观组图谱。
including genes, and low DNA methylation levels. A comparison across sub-genomes reveals that evolutionary selection on gene regulation is targeted at the sequence and chromatin feature levels. The divergent enrichment of cis-elements between enhancer-like sequences and promoters implies these functional elements are targeted by different transcription factors. Conclusions
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